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Saturday, September 23, 2023

Well being good points from uncommon illness, specialty and expedited overview medication – Healthcare Economist

James Chambers has put collectively a sequence of papers taking a look at well being good points (and value effectiveness) utilizing the Tufts Value Effectiveness Evaluation Registry. In these research , he finds that remedies for uncommon ailments, specialty medication, and people who obtain expedited overview are extra doubtless to offer the biggest well being profit (≥0.9 QALYs gained versus comparator).

Chambers et al. (2020) exhibits that is true for remedies for uncommon illness:

Chambers et al. (2017) exhibits that is true for remedies receiving expedited overview:

and Chambers et al. (2014) exhibits that that is true for specialty medication.

Word that the bigger well being good points are sometimes correlated with increased drug costs. Within the case of uncommon illness, these extremely useful remedies are much less prone to be value efficient, because of excessive remedy value. This shouldn’t be stunning, nonetheless, as increased costs are wanted to fund R&D efforts since–by definition–market sizes are smaller for uncommon ailments. Then again the Chambers et al. (2014) examine exhibits that whereas specialty medication value extra, value effectiveness is corresponding to conventional medication as a result of well being good points are increased on common.

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